Vitamin D Receptor–Dependent Signaling Protects Mice From Dextran Sulfate Sodium-Induced Colitis
نویسندگان
چکیده
منابع مشابه
Vitamin D regulates the gut microbiome and protects mice from dextran sodium sulfate-induced colitis.
The active form of vitamin D [1,25-dihydroxycholecalciferol, 1,25(OH)2D3] and the vitamin D receptor (VDR) regulate susceptibility to experimental colitis. The effect of the bacterial microflora on the susceptibility of C57BL/6 mice to dextran sodium sulfate-induced colitis was determined. Mice that cannot produce 1,25(OH)2D3 [Cyp27b1 (Cyp) knockout (KO)], VDR KO as well as their wild-type litt...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2017
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2016-1913